Title: Simulation of Floating Point FFT Algorithm for Characteristic Frequency Calculation of Protein Family


Volume 9 Issue 1 Year 2019

Authors:

Harshit Mathur

ijskit@skit.ac.in
Department of Electronics & Communication Engineering, Swami Keshvanand Institute of Technology, Management and Gramothan, Jaipur-302017 (INDIA),

vikas Pathak

vikaspathak85@gmail.com
Department of Electronics & Communication Engineering, Swami Keshvanand Institute of Technology, Management and Gramothan, Jaipur-302017 (INDIA),

Yamini Rathore

ijskit@skit.ac.in
Department of Electronics & Communication Engineering, Swami Keshvanand Institute of Technology, Management and Gramothan, Jaipur-302017 (INDIA)

Pages: 45-52


Abstract:

The objective of this paper is to implement the 256 point 32-bit floating point FFT algorithm for characteristic frequency calculation of protein family. This characteristics frequency can be further used for finding the location of hotspots in any particular protein of that family. Arithmetic adder/subtractor,
and multiplier based on single precision IEEE-754 standards are designed. Simulation result of this FFT algorithm on Xilinx ISE tool is verified with
MATLAB software and found similar result for calculation of characteristic frequency of protein family. Once the characteristic frequency for the
particular biological function or interaction is determined, the individual "hot spot" amino acids are identified and possible to observe biological behavior
of the protein. The VLSI architecture of 256-point FFT algorithm based on floating point data has been designed and synthesized using Xilinx ISE 14.4 tool
for ARTIX-7 FPGA and simulated using Xilinx Isim simulator with the help of VHDL programming.

Keywords:
VHDL, FFT, DIT, Radix-2, IEEE-754, Genomics, Protein, Hot-spot Region, DFT