Selecting the proper dielectric material as a substrate is vital in the construction of a Microstrip slot antenna. By choosing the right substrate material, it is possible to overcome the drawbacks of microstrip antennas, such as low efficiency, high Return Loss (S11), and Low Gain. This is because the substrate's permittivity is a crucial factor in regulating the antenna efficiency, radiation pattern and antenna gain. This paper presents various substrates for a slotted compact microstrip antenna. Various substrate variations are used in the current work, which is done for wireless applications. In terms of dielectric constant and loss tangent, the substrate materials have two fundamental characteristics. Coaxial probe feeding is employed in the proposed design. It is explored in detail how different types of dielectric materials affect slotted structures in terms of radiation properties like resonating frequency, Gain, Return loss (S11), Current distribution, Radiation pattern. Here, zero loss tangent dielectric materials have been chosen.